Comet Calendar Event Details

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Physics Colloquium: Multiscale Modeling in Molecular Biophysics: From Simple Liquids to Macromolecular Design
Monday, Feb. 17
1 p.m. - 2 p.m. Location: PHY 1.606

Dr. Sergio Hassan (National Institutes of Health)

At the molecular level, all biological systems operate through a reduced set of physical mechanisms, which are common across organisms in both normal and pathological states. After an overview of my recent work on topics as varied (in a biological sense) as neurodegeneration, human reproduction, pain control, and drug abuse, I will focus on my efforts to model the physics of biomolecular interactions in complex media, including the intracellular fluid and the blood plasma. I will then show how the insight gained from these studies can be combined with pattern recognition techniques to design synthetic nanostructures that interact with biological matter in specific ways. I will describe a method based on artificial neural networks for reverse engineering such particles and will show how arrays of networks can be interconnected to incorporate (by necessity) increasing levels of complexity in the design. I will discuss the implications for diagnostics and therapeutics and the potential impact in the emerging fields of theranostics and precision medicine.

Persons with disabilities may submit a request for accommodations to participate in this event at UT Dallas' ADA website. You may also call (972) 883-5331 for assistance or send an email to [email protected]. All requests should be received no later than 2 business days prior to the event.
Contact Info:
Michael Kesden, 972-883-3598
Questions? Email me.

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