We focus on integrating nanoscale elements of electronics, chemistry, and biology. Such nano-bio-engineering fusion may provide rare opportunities to explore new science and applications
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Lithographic Nanofabrication
"Top-down" or nanolithographic fabrication based on e-beam lithography and nanoimprint lithography is applied to make single digit (2-10 nm) low-dimensional structures with size comparable to chemical synthesis, but with better controlability and uniformity. We also investigate material property, metrology, and "strange" phenomena emerged with these nanostructures.
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Publications: Trivedi 2011, Trivedi 2009, Trivedi 2009(2), Tao 2008. Hu 2005, Hu 2004
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Si NanoWire Electronic Biosensor
Si nanowires field effect transistors (FETs) are fabricated using CMOS process on Si-on-insulator wafers. Chemical receptors are anchored on these SiNWs for label-free detection of biospecies for a wide-range of applications, e.g. disease diagnostics and enviromental monitoring. Advantages of nanoelectronic biosensor is its ultrasensitivity, real time, low cost, and small form factor.
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Examplary Publications: Tian 2011, Regonda 2008 |
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Nanoimprinted Organic Solar Cells
We use nanoimprint to create an optimal nano-morphology of vertically interdigitized and bi-continuous donor and acceptor materials for high efficiency in organic solar cells. Nanoimprint can simutaneously control the morphology and chain alignments in polymer, which is a challenge for chemical methods. We are also developing rollable nano-printing to enable low cost fab.
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| Publications: Yang 2010, Zhou 2010, Aryal 2009. Trivedi 2009, Aryal 2008 |
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Biomaterials for Nanomedicine
Combination of top-down nanoimprint lithography and bottom-up self-assembly is developed to make uniform and shape-specific polymer nanoparticles for nanomedicine applications. Molecular agents and drugs can be encapsulated in these polymer nanoparticle platforms for targetted delivery and imaging. We also develop jet roller nanoprinting tool for high-throughput particle production.
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Publications: Tao 2011, Tao 2010, Buyukserin 2009, Tao 2007 |
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Nanostructures for Tissue Engin.
Nanoimprint is used to make nanogratings as scaffolds for tissue engineering. By elongating pillars during mold release, very high aspect ratio pillars like nano-grass are made. Gratings can guide cell alignment and elongation, while nano-grass strongly inhibits cell adhesion despite of surface chemistry. These nanoscaffolds serve as a testbed to study cell-substratrum interaction at the nanoscale.
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Publications: Hu 2010, Crouch 2009, Hu 2005
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