Raimund J. Ober, Ph.D.
Professor
Department of Electrical Engineering
University of Texas at Dallas

Adjunct Professor
University of Texas Southwestern Medical Center at Dallas

Research Interests
Our research interests involve the development and use of bionanotechnology approaches to the study of biological problems. In particular, we work on experimental and image processing approaches to fluorescence microscopy with a specific emphasis on the detection of single molecules.  Our work on biosensors concerns development of improved experimental and data analysis approaches for the study protein-protein interactions. The biological questions that we study in collaboration with Prof. E.S. Ward at UT Southwestern Medical Center at Dallas deal with immunological problems such as the question of how the dynamics, transport and distribution of antibodies are regulated in vivo. To this end, for example, the trafficking of antibody molecules is imaged by fluorescence microscopy in a live cell environment.

The engineering aspects of the research involve the development of advanced analytical tools, software and instrumentation.  Recently, we have, for example, investigated the accuracy with which important parameters can be determined from experiments using information theoretic methods.